David H Vandorpe Selected Research

Grammostola spatulata MTx4 protein

1/2022	Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes.
1/2010	Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

David H Vandorpe Research Topics

Disease

3	Nephrolithiasis 01/2016 - 03/2008
2	Sickle Cell Anemia (Hemoglobin S Disease) 01/2022 - 12/2021
2	Hypoxia (Hypoxemia) 01/2022 - 01/2010
2	hereditary Xerocytosis 01/2019 - 01/2017
2	Anemia 01/2014 - 05/2011
2	Autosomal Dominant Polycystic Kidney (ADPKD) 08/2005 - 02/2002
1	Hereditary Spherocytosis 10/2021
1	Cystitis 01/2020
1	Dehydration (Water Stress) 01/2019
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2019
1	Hyperoxaluria (Oxaluria) 01/2016
1	Cystic Fibrosis (Mucoviscidosis) 08/2011
1	Diastrophic dysplasia 06/2010
1	Macular Degeneration (Age-Related Maculopathy) 12/2005
1	Insulin Resistance 12/2005
1	Neoplasms (Cancer) 12/2005
1	Choroidal Neovascularization 12/2005

Drug/Important Bio-Agent (IBA)

9	CationsIBA 01/2022 - 02/2002
3	AnionsIBA 01/2016 - 03/2008
2	Grammostola spatulata MTx4 proteinIBA 01/2022 - 01/2010
2	OxalatesIBA 06/2010 - 03/2008
1	Suramin (Suramin Sodium)IBA 01/2022
1	Probenecid (Benemid)FDA LinkGeneric 01/2022
1	AcidsIBA 01/2022
1	Adenosine Triphosphate (ATP)IBA 01/2022
1	Apyrase (ATP Diphosphatase)IBA 01/2022
1	Ketamine FDA LinkGeneric 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	TRPC6 Cation ChannelIBA 01/2019
1	senicapocIBA 01/2017
1	Carbon MonoxideIBA 01/2010
1	Peptides (Polypeptides)IBA 03/2008
1	Appetite Depressants (Anorectics)IBA 12/2005
1	squalamineIBA 12/2005
1	Angiogenesis InhibitorsIBA 12/2005
1	Proteins (Proteins, Gene)FDA Link 02/2002